Doxycycline – Versatile tetracycline antibiotic for infections and acne.
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What is Doxycycline?
Doxycycline is a broad-spectrum tetracycline antibiotic used to treat a wide variety of bacterial infections. It’s particularly well-known for treating acne, chest infections, and certain sexually transmitted infections.
Book an online consultation to discuss whether Doxycycline is suitable for your condition. Our qualified GPs can provide expert advice and prescriptions when clinically appropriate.
What is Doxycycline used for?
- Acne and rosacea treatment
- Chest infections (pneumonia, bronchitis)
- Urinary tract infections
- Sexually transmitted infections (chlamydia, gonorrhoea)
- Malaria prevention (travel)
- Lyme disease
- Skin and soft tissue infections
How does Doxycycline work?
A tetracycline antibiotic that inhibits bacterial protein synthesis, preventing bacteria from growing and multiplying.
Dosage and Administration
Adults
100-200 mg daily, usually taken once or twice daily with food.
Children
Not recommended for children under 12 years due to risk of tooth discoloration.
Important Notes
- Take with plenty of water while sitting or standing upright.
- Avoid lying down for 30 minutes after taking.
- Take with food to reduce stomach upset.
- Avoid dairy products, iron supplements, and antacids within 2 hours.
Side Effects
Common Side Effects
- Nausea and vomiting
- Diarrhoea
- Stomach upset
- Increased sensitivity to sunlight
- Headache
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe oesophageal irritation or ulceration
- Severe skin reactions to sunlight
- Signs of liver problems (yellowing of skin/eyes)
- Severe headache with vision changes
Important Warnings
- Avoid direct sunlight and use high SPF sunscreen—increases sun sensitivity.
- Not suitable for pregnant women, breastfeeding mothers, or children under 12.
- Do not lie down for at least 30 minutes after taking to prevent oesophageal irritation.
- Tell your GP if you have liver or kidney problems.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Antacids, iron supplements, and dairy products – reduce absorption.
- Warfarin – may enhance anticoagulant effects.
- Oral contraceptives – may reduce effectiveness.
- Retinoids (acne medications) – increased risk of raised intracranial pressure.
- Cyclosporine – may increase cyclosporine toxicity.
Frequently Asked Questions
Why can't children take Doxycycline?
Doxycycline can cause permanent tooth discoloration and affect bone development in children under 12 years old.
How long does it take to work for acne?
You may see improvement in acne after 6-8 weeks of treatment, though some people notice changes sooner.
Can I drink alcohol while taking Doxycycline?
Small amounts of alcohol are generally okay, but excessive drinking may reduce the medication's effectiveness and increase side effects.
Why must I avoid dairy products?
Calcium in dairy products can bind to Doxycycline and reduce its absorption, making it less effective.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14