Fucidin – Potent topical antibiotic for skin infections and wounds.
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What is Fucidin?
Fucidin (fusidic acid) is a highly effective topical antibiotic with a unique mechanism of action that makes it particularly valuable for treating skin infections caused by staphylococci and streptococci. Its excellent skin penetration and specific activity against common skin bacteria make it a first-choice treatment for many bacterial skin conditions.
Book an online consultation if you have signs of skin infection such as spreading redness, pus-filled spots, infected cuts or wounds, or skin conditions that appear to be getting infected. Our GPs can assess your skin condition and determine if Fucidin or other antibiotic treatments are appropriate for your specific infection.
What is Fucidin used for?
- Impetigo
- Infected eczema
- Infected wounds and cuts
- Secondary bacterial skin infections
- Folliculitis
- Infected insect bites
- Skin infections caused by staphylococci
How does Fucidin work?
A unique antibiotic that inhibits bacterial protein synthesis by blocking elongation factor G, specifically targeting gram-positive bacteria (especially staphylococci and streptococci) commonly found in skin infections.
Dosage and Administration
Adults
Apply thin layer to affected area 3-4 times daily. Continue for 48 hours after infection clears, usually 7-10 days total.
Children
Same as adults—safe for use in children and infants. Apply sparingly to affected areas only.
Important Notes
- Apply thin layer and rub in gently.
- Wash hands thoroughly before and after application.
- Continue treatment for 48 hours after infection appears cleared.
- Do not use for more than 10 days without medical review.
Side Effects
Common Side Effects
- Local skin irritation
- Stinging or burning on application
- Contact dermatitis
- Itching at application site
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe allergic reactions (rare)
- Widespread skin sensitization
- Secondary fungal infections (with prolonged use)
Important Warnings
- Avoid contact with eyes and mucous membranes.
- Do not use for more than 10 days to prevent bacterial resistance.
- Tell your GP if condition worsens or doesn't improve within 7 days.
- Use sparingly to minimize risk of developing bacterial resistance.
- Not effective against fungal or viral skin infections.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Generally no significant systemic interactions due to topical use.
- May reduce effectiveness if used with other topical antibiotics.
- No significant interactions with oral medications.
Frequently Asked Questions
How is Fucidin different from other antibiotic creams?
Fucidin (fusidic acid) has a unique mechanism of action and is particularly effective against staphylococci, which are common causes of skin infections. It's often more effective than other topical antibiotics for these infections.
Can I use Fucidin on open wounds?
Yes, it's specifically designed for infected wounds and cuts. Apply a thin layer to the infected area and surrounding skin.
Why shouldn't I use Fucidin for more than 10 days?
Prolonged use can lead to bacterial resistance, making the antibiotic less effective. Most skin infections should clear within 7-10 days with proper treatment.
Can I use Fucidin with other skin treatments?
Generally yes, but space them apart by at least 30 minutes. However, check with your GP about combining with other prescription treatments.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14