Fusidic Acid – Topical antibiotic for skin and eye bacterial infections.
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What is Fusidic Acid?
Fusidic acid is a highly effective topical antibiotic that’s particularly valuable for treating Staphylococcal skin infections, including some resistant strains. It’s available as both skin cream and eye drops, making it versatile for treating bacterial infections in different body areas.
Book an online consultation if you have persistent skin infections, suspected bacterial conjunctivitis, or skin conditions that may be infected. Our GPs can assess your symptoms and determine if Fusidic acid or other topical treatments are appropriate for your specific condition.
What is Fusidic Acid used for?
- Bacterial skin infections
- Impetigo
- Infected eczema
- Folliculitis
- Bacterial conjunctivitis (eye infections)
- Infected cuts and wounds
- Staphylococcal skin infections
- Post-surgical wound infections
How does Fusidic Acid work?
A bacteriostatic antibiotic that inhibits bacterial protein synthesis by blocking elongation factor G, particularly effective against Staphylococcus aureus including some MRSA strains.
Dosage and Administration
Adults
Apply thinly to affected area 3-4 times daily. For eyes: apply small amount to lower eyelid 2-3 times daily.
Children
Same dosage as adults—safe for use in children and babies.
Important Notes
- Apply to clean, dry skin or clean eyes.
- Wash hands before and after application.
- For eye infections: pull down lower eyelid and apply small amount.
- Continue for 48 hours after symptoms resolve.
Side Effects
Common Side Effects
- Mild skin irritation
- Burning or stinging (especially in eyes)
- Local allergic reactions
- Skin redness
- Itching at application site
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe allergic reactions (rare)
- Persistent skin irritation
- Worsening of infection
- Eye irritation or pain (with eye preparations)
Important Warnings
- For external use only—do not swallow or apply to large areas of broken skin.
- Avoid contact with eyes when using skin preparations.
- Do not use for more than 7 days without medical review.
- Tell your GP if condition worsens or doesn't improve within 2-3 days.
- Not suitable for viral or fungal infections.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Generally no significant interactions with topical use.
- Minimal systemic absorption with normal topical application.
- Safe to use with most other medications.
- Avoid mixing with other topical medications at the same site.
Frequently Asked Questions
How quickly does Fusidic acid work?
You should see improvement within 2-3 days for skin infections. Eye infections often improve within 1-2 days. Complete the full course even if symptoms improve.
Can I use Fusidic acid on open wounds?
Yes, it can be used on minor cuts and wounds, but avoid large areas of broken skin. For significant wounds, seek medical advice first.
Is Fusidic acid effective against MRSA?
Fusidic acid is effective against some MRSA strains, making it valuable when other topical antibiotics have failed, but resistance can develop.
Can I use it on my baby's skin?
Yes, Fusidic acid is safe for babies and children. It's commonly used for impetigo and infected eczema in pediatric patients.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14