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Hydrocortisone – Mild topical steroid for skin inflammation and eczema.

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What is Hydrocortisone?

Hydrocortisone is the mildest and safest topical steroid available, making it ideal for treating various inflammatory skin conditions including eczema, contact dermatitis, and allergic reactions. Its excellent safety profile allows for use in children and sensitive areas when other steroids might be too strong.

Book an online consultation if you’re experiencing persistent skin inflammation, eczema flares, or allergic skin reactions that may benefit from topical steroid treatment. Our GPs can assess your skin condition and determine if Hydrocortisone or other topical treatments are appropriate for your specific needs.

What is Hydrocortisone used for?

  • Eczema and dermatitis
  • Contact allergic reactions
  • Insect bites and stings
  • Mild psoriasis
  • Seborrheic dermatitis
  • Anal itching (hemorrhoids)
  • Minor skin irritations
  • Post-inflammatory hyperpigmentation

How does Hydrocortisone work?

A mild topical corticosteroid that reduces inflammation, itching, and redness by suppressing the local immune response and reducing inflammatory mediator release in the skin.

Dosage and Administration

Adults

Apply thinly to affected area 1-2 times daily. Available as 0.5%, 1%, and 2.5% creams and ointments.

Children

Safe for use in children—apply thinly once or twice daily under medical guidance.

Important Notes

  • Apply thinly to clean, dry skin.
  • Gently rub in until fully absorbed.
  • Wash hands after application unless treating hands.
  • Use for short periods—typically 7-14 days maximum without medical review.

Side Effects

Common Side Effects

  • Mild burning or stinging (initial application)
  • Skin dryness
  • Local irritation
  • Temporary skin lightening

Serious Side Effects

Seek immediate medical attention if you experience:

  • Skin thinning (with prolonged use)
  • Stretch marks (with prolonged use)
  • Contact dermatitis (allergic reaction)
  • Skin infections (masking or worsening)
  • Systemic absorption effects (rare with normal use)

Important Warnings

  • Do not use on infected skin unless combined with appropriate antimicrobial treatment.
  • Avoid prolonged use on face, groin, or skin folds where absorption is higher.
  • Do not use for more than 2 weeks continuously without medical review.
  • Not suitable for viral skin infections like cold sores or chickenpox.
  • Minimize use during pregnancy and breastfeeding.

Drug Interactions

Tell your GP if you're taking any of the following medications:

  • Generally minimal interactions due to topical application.
  • Avoid applying with other topical medications unless advised.
  • May reduce effectiveness of topical antibiotics if used simultaneously.
  • Generally safe to use with oral medications.

Frequently Asked Questions

How long can I safely use Hydrocortisone cream?

For mild conditions, up to 2 weeks continuously is generally safe. For chronic conditions like eczema, intermittent use under medical supervision is recommended.

Can I use Hydrocortisone on my face?

Yes, but with caution and for shorter periods (maximum 5-7 days) as facial skin is more sensitive and absorbs medication more readily.

Is Hydrocortisone safe for babies?

Yes, mild hydrocortisone (0.5-1%) is safe for babies with eczema when used appropriately. Always follow pediatric dosing guidelines and duration limits.

Why is Hydrocortisone considered 'mild' compared to other steroids?

Hydrocortisone is the weakest topical steroid (Class 1), making it safer for long-term use, sensitive areas, and children, while still being effective for mild inflammation.

Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14