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Hyoscine Butylbromide – Effective antispasmodic for stomach cramps and IBS symptoms.

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What is Hyoscine Butylbromide?

Hyoscine butylbromide (Buscopan) is a highly effective antispasmodic medication that provides rapid relief from stomach cramps, bowel spasms, and IBS symptoms. It’s particularly valued for its quick onset of action and excellent safety profile.

Book an online consultation if you’re experiencing persistent stomach cramps, IBS symptoms, or other abdominal pain that may benefit from antispasmodic treatment. Our GPs can assess your symptoms and determine if Buscopan or other treatments are appropriate for your digestive health needs.

What is Hyoscine Butylbromide used for?

  • Irritable bowel syndrome (IBS) symptoms
  • Stomach cramps and spasms
  • Bowel spasms
  • Menstrual cramps
  • Bladder spasms
  • Diagnostic procedures (to reduce bowel movement)
  • Gallbladder spasms
  • Kidney stone pain (as adjunct)

How does Hyoscine Butylbromide work?

An antispasmodic that blocks muscarinic receptors in smooth muscle, reducing muscle spasms and contractions in the digestive system, bladder, and reproductive organs.

Dosage and Administration

Adults

10-20 mg taken 3-4 times daily. Maximum 80 mg daily. Can also be given by injection in hospital.

Children

Children 6-12 years: 10 mg up to 3 times daily. Under 6 years: specialist advice required.

Important Notes

  • Can be taken with or without food.
  • Take when needed for cramps, or regularly for IBS.
  • Works quickly—usually within 15-30 minutes.
  • Can be used as needed or on a regular schedule.

Side Effects

Common Side Effects

  • Dry mouth
  • Constipation
  • Dizziness
  • Blurred vision
  • Fast heart rate
  • Skin rash (mild)

Serious Side Effects

Seek immediate medical attention if you experience:

  • Severe allergic reactions
  • Severe constipation or bowel obstruction
  • Difficulty urinating
  • Confusion (especially in elderly)
  • Severe skin reactions (rare)

Important Warnings

  • Tell your GP if you have glaucoma, enlarged prostate, or severe heart disease.
  • Not suitable for people with myasthenia gravis or severe ulcerative colitis.
  • Use with caution in hot weather—reduced sweating may cause overheating.
  • May cause drowsiness or dizziness—avoid driving until you know how it affects you.
  • Generally very safe when used as directed.

Drug Interactions

Tell your GP if you're taking any of the following medications:

  • Other anticholinergic drugs—may increase side effects like dry mouth and constipation.
  • Tricyclic antidepressants—additive anticholinergic effects.
  • Generally few significant drug interactions.
  • Safe to use with most other medications.

Frequently Asked Questions

How quickly does Buscopan work for stomach cramps?

Buscopan usually starts working within 15-30 minutes of taking a tablet, providing rapid relief from stomach cramps and spasms.

Can I take Buscopan regularly for IBS?

Yes, it can be taken regularly for IBS symptoms or just when needed for cramps. Many people find taking it before meals helpful for preventing symptoms.

Is Buscopan safe for menstrual cramps?

Yes, it's effective for menstrual cramps and can be used alongside painkillers like ibuprofen or paracetamol for better pain relief.

Can I buy Buscopan without a prescription?

Basic Buscopan tablets are available over-the-counter, but higher strength versions and other formulations require a prescription.

Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14