Ivermectin – Antiparasitic medication for scabies and worm infections.
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What is Ivermectin?
Ivermectin is a highly effective antiparasitic medication that’s particularly valuable for treating scabies when topical treatments haven’t worked, and for various parasitic worm infections. It’s considered the gold standard treatment for several parasitic conditions.
Book an online consultation if you suspect you have scabies, have been diagnosed with a parasitic infection, or have persistent itching that may be due to parasites. Our GPs can assess your symptoms and determine if Ivermectin treatment is appropriate for your specific condition.
What is Ivermectin used for?
- Scabies (when topical treatments have failed)
- Strongyloidiasis (threadworm infection)
- Onchocerciasis (river blindness)
- Lymphatic filariasis
- Crusted scabies in immunocompromised patients
- Head lice (when other treatments fail)
- Rosacea (topical form)
How does Ivermectin work?
An antiparasitic agent that binds to glutamate-gated chloride channels in invertebrates, causing paralysis and death of parasites. It has minimal effect on mammalian cells.
Dosage and Administration
Adults
200 micrograms per kg body weight as a single dose, repeated after 1-2 weeks if needed.
Children
Weight-based dosing: 200 micrograms per kg—not recommended for children under 15 kg.
Important Notes
- Take on an empty stomach with water.
- Usually given as a single dose or two doses 1-2 weeks apart.
- For scabies, all household members may need treatment.
- Follow up with GP to ensure treatment success.
Side Effects
Common Side Effects
- Dizziness
- Nausea
- Diarrhoea
- Skin rash
- Fatigue
- Abdominal pain
- Loss of appetite
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe skin reactions
- Low blood pressure
- Severe allergic reactions
- Neurological effects (confusion, seizures)
- Eye problems (with high doses)
- Liver problems (rare)
Important Warnings
- Not recommended for children weighing less than 15 kg or pregnant/breastfeeding women.
- Tell your GP if you have liver disease or are taking other medications.
- May cause dizziness—avoid driving or operating machinery for 24 hours.
- For scabies, continue to use prescribed topical treatments as directed.
- Not proven effective or safe for COVID-19 despite some claims.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Warfarin—may increase bleeding risk.
- Barbiturates—may reduce ivermectin effectiveness.
- Benzodiazepines—may increase sedative effects.
- Generally few significant drug interactions.
- Alcohol—may increase dizziness and nausea.
Frequently Asked Questions
How effective is Ivermectin for scabies?
Ivermectin is highly effective for scabies, especially when topical treatments have failed. Cure rates are typically 95% or higher with appropriate dosing.
Why is Ivermectin usually given as a single dose?
Ivermectin has a long half-life and persists in the body for weeks, making a single dose or two doses sufficient to eliminate most parasitic infections.
Can I use Ivermectin to prevent or treat COVID-19?
No, current evidence does not support using Ivermectin for COVID-19. It should only be used for proven parasitic infections under medical supervision.
Will other people in my household need treatment for scabies?
Yes, usually all household members and close contacts need treatment simultaneously to prevent reinfection, even if they don't have symptoms.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14