Lisinopril – ACE inhibitor for blood pressure control and heart protection.
Get expert medical advice and same-day prescriptions from qualified UK doctors through our secure online consultation platform.
- Professional online consultation and prescription
- Same-day service when clinically appropriate
- Secure delivery to your chosen pharmacy
Secure Telehealth Platform Trusted by Over 150,000 Patients
What is Lisinopril?
Lisinopril is a highly effective ACE inhibitor that provides excellent blood pressure control while offering additional cardiovascular and kidney protection. It’s particularly valuable for patients with diabetes, heart failure, or those who’ve had heart attacks, providing benefits beyond just blood pressure reduction.
Book an online consultation if you have high blood pressure, heart failure symptoms, diabetes with kidney concerns, or need cardiovascular risk assessment. Our GPs can evaluate your blood pressure and overall cardiovascular health to determine if Lisinopril or other blood pressure medications are appropriate for your specific condition.
What is Lisinopril used for?
- High blood pressure (hypertension)
- Heart failure
- Post-heart attack cardioprotection
- Diabetic kidney disease protection
- Chronic kidney disease
- Prevention of cardiovascular events
- Left ventricular dysfunction
How does Lisinopril work?
An ACE (Angiotensin Converting Enzyme) inhibitor that blocks the formation of angiotensin II, a hormone that narrows blood vessels. This leads to vasodilation, reduced blood pressure, and decreased workload on the heart.
Dosage and Administration
Adults
Starting dose: 2.5-10mg once daily. Maintenance: 10-40mg once daily depending on condition and response.
Children
Specialist supervision required—dosing based on weight and specific condition.
Important Notes
- Take at the same time each day, with or without food.
- Start with low dose and increase gradually as directed.
- Regular blood pressure and kidney function monitoring required.
- May take several weeks to see full blood pressure benefits.
Side Effects
Common Side Effects
- Dry persistent cough
- Dizziness or lightheadedness
- Headache
- Fatigue
- Nausea
- Low blood pressure symptoms
- Increased potassium levels
Serious Side Effects
Seek immediate medical attention if you experience:
- Angioedema (swelling of face, lips, tongue, throat)
- Severe drop in blood pressure
- Kidney problems
- Hyperkalemia (dangerous potassium levels)
- Severe allergic reactions
- Liver problems (rare)
Important Warnings
- Tell your GP immediately if you develop swelling of face, lips, or throat.
- Regular monitoring of kidney function and potassium levels required.
- Avoid potassium supplements and salt substitutes unless advised.
- May cause dizziness—avoid driving until you know how it affects you.
- Tell your GP if you're pregnant or planning pregnancy—not safe in pregnancy.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Potassium supplements and salt substitutes—risk of dangerous potassium levels.
- NSAIDs (ibuprofen, diclofenac)—may reduce effectiveness and affect kidneys.
- Lithium—may increase lithium levels.
- Diuretics—may cause excessive blood pressure drop.
- Diabetes medications—may enhance blood sugar lowering.
Frequently Asked Questions
Why do I get a persistent cough with Lisinopril?
About 10-15% of people develop a dry cough due to increased bradykinin levels. If troublesome, your GP may switch you to an ARB (like Losartan) which has similar benefits without the cough.
How long does it take for Lisinopril to lower blood pressure?
You may see some effect within hours, but full blood pressure benefits typically take 2-4 weeks of regular use.
Can I stop taking Lisinopril suddenly?
No, stopping suddenly can cause a rebound increase in blood pressure. Your GP will provide a gradual reduction plan if needed.
Why do I need regular blood tests while taking Lisinopril?
To monitor kidney function and potassium levels, as ACE inhibitors can affect both. This ensures the medication remains safe for you.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14