Lymecycline – Long-acting tetracycline antibiotic for acne and infections.
Get expert medical advice and same-day prescriptions from qualified UK doctors through our secure online consultation platform.
- Professional online consultation and prescription
- Same-day service when clinically appropriate
- Secure delivery to your chosen pharmacy
Secure Telehealth Platform Trusted by Over 150,000 Patients
What is Lymecycline?
Lymecycline is a highly effective tetracycline antibiotic that’s particularly valuable for treating moderate to severe acne due to its excellent skin penetration and anti-inflammatory properties. Its once-daily dosing makes it convenient for long-term acne treatment while maintaining effectiveness against bacterial infections.
Book an online consultation if you’re struggling with persistent acne, need antibiotic treatment for bacterial infections, or require assessment for long-term acne management. Our GPs can evaluate your skin condition and determine if Lymecycline or other acne treatments are appropriate for your specific situation.
What is Lymecycline used for?
- Moderate to severe acne
- Respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
- Chlamydia infections
- Mycoplasma infections
- Long-term acne treatment
How does Lymecycline work?
A tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing bacterial growth. It also has anti-inflammatory properties that make it particularly effective for acne treatment.
Dosage and Administration
Adults
Standard dose: 408mg once daily. Severe infections: 408mg twice daily. Take on an empty stomach with a full glass of water.
Children
Not recommended under 12 years due to tooth discoloration risk. 12+ years: adult dose if weight appropriate.
Important Notes
- Take on an empty stomach, 1 hour before or 2 hours after meals.
- Take with a full glass of water while standing/sitting upright.
- Avoid dairy products, antacids, and iron supplements for 2 hours before/after.
- Continue for full course even if symptoms improve.
Side Effects
Common Side Effects
- Nausea and stomach upset
- Diarrhoea
- Headache
- Dizziness
- Photosensitivity (increased sun sensitivity)
- Vaginal thrush
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe diarrhoea (C. difficile infection)
- Oesophageal ulceration
- Severe allergic reactions
- Benign intracranial hypertension
- Liver problems
- Blood disorders (rare)
Important Warnings
- Not suitable for pregnant women or children under 12—can cause tooth discoloration.
- Increases sun sensitivity—use strong sunscreen and avoid prolonged sun exposure.
- Take with plenty of water and remain upright for 30 minutes to prevent oesophageal irritation.
- Tell your GP if you develop severe headaches or vision problems.
- Can reduce effectiveness of oral contraceptives—use additional contraception.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Oral contraceptives—may reduce effectiveness, use additional contraception.
- Warfarin—may enhance anticoagulant effects.
- Retinoids (isotretinoin)—increased risk of benign intracranial hypertension.
- Dairy products, antacids, iron—significantly reduce absorption.
- Ciclosporin—may increase ciclosporin toxicity.
Frequently Asked Questions
How long does it take for Lymecycline to work for acne?
You may see some improvement in 6-8 weeks, but full benefits often take 3-4 months of consistent use. Continue taking as prescribed even if initial improvement seems slow.
Why do I need to avoid dairy products with Lymecycline?
Calcium in dairy products binds to the antibiotic, preventing its absorption. This significantly reduces effectiveness, so take 2 hours away from dairy.
Can I take Lymecycline long-term for acne?
Yes, it's commonly used for 3-6 months or longer for acne treatment. Your GP will monitor you and may combine it with topical treatments for best results.
Why am I more sensitive to sunlight while taking Lymecycline?
Tetracyclines increase photosensitivity, making you more prone to sunburn. Always use SPF 30+ sunscreen and limit sun exposure during treatment.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14