Trimovate – Triple-action cream for infected inflammatory skin conditions.
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What is Trimovate?
Trimovate is a specialized combination cream that provides triple-action treatment for infected inflammatory skin conditions. It’s particularly useful when there’s uncertainty about whether an infection is bacterial, fungal, or both, while also treating the underlying inflammation.
Book an online consultation if you have infected eczema, persistent skin inflammation, or skin conditions that haven’t responded to single-ingredient treatments. Our GPs can assess whether Trimovate’s combination approach is appropriate for your specific skin condition.
What is Trimovate used for?
- Infected eczema
- Infected dermatitis
- Secondary bacterial or fungal skin infections
- Inflamed skin conditions with mixed infections
- Nappy rash with infection
- Intertrigo (skin fold infections)
- Post-surgical wound infections (superficial)
How does Trimovate work?
A combination cream containing clobetasone butyrate (mild steroid), oxytetracycline (antibiotic), and nystatin (antifungal), providing anti-inflammatory, antibacterial, and antifungal effects simultaneously.
Dosage and Administration
Adults
Apply thinly to affected area 2-3 times daily. Do not use for more than 7 days without medical review.
Children
Can be used in children over 2 years under medical supervision—apply thinly and sparingly.
Important Notes
- Apply thinly to clean, dry skin.
- Do not use on large areas of skin or for prolonged periods.
- Wash hands after application unless treating hands.
- Avoid contact with eyes and mucous membranes.
Side Effects
Common Side Effects
- Skin irritation or burning
- Dryness at application site
- Skin thinning (with prolonged use)
- Local allergic reactions
- Change in skin pigmentation
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe allergic reactions
- Skin atrophy (thinning) and stretch marks
- Delayed wound healing
- Masking of skin infections
- Systemic absorption effects (rare with normal use)
- Contact dermatitis
Important Warnings
- Do not use for more than 7 days without medical review.
- Not suitable for viral skin infections, acne, or rosacea.
- Avoid use on broken or severely damaged skin.
- Tell your GP if condition worsens or doesn't improve within 7 days.
- Use with caution on face, genitals, or skin folds—higher absorption.
Drug Interactions
Tell your GP if you're taking any of the following medications:
- Generally minimal systemic absorption with topical use.
- Avoid using with other topical steroids simultaneously.
- May interact with other topical medications applied to the same area.
- Generally safe to use with oral medications.
Frequently Asked Questions
Why does Trimovate contain three different medications?
The combination treats inflammation (steroid), bacterial infection (antibiotic), and fungal infection (antifungal) simultaneously, making it ideal for infected inflammatory skin conditions.
How long can I safely use Trimovate?
It should not be used for more than 7 days without medical review due to the steroid content, which can cause skin thinning with prolonged use.
Can I use Trimovate on my face?
It can be used on the face under medical supervision, but with extra caution as facial skin is more sensitive and absorbs medication more readily.
What should I do if my skin condition gets worse?
Stop using Trimovate and contact your GP immediately, as worsening may indicate the wrong diagnosis or an allergic reaction to the treatment.
Medically Reviewed by: Mohammed Hassan - Independent Prescriber
Last Updated: 2025-01-14